Could Leptin Eliminate Type 1 Diabetes?

For years it has been stated that there is no truly effective treatment for type 1 or juvenile diabetes, nor is there a cure.  Children and young people with the disease have simply had to depend on insulin injections from the time that they are diagnosed, and have had to depend on the injections for their entire lives. 

There is good news regarding the treatment and cure of type 1 diabetes that has just come to light.  Scientists that have been working with rodents that have diabetes and are terminally ill because of it, have found that when they injected the rodents with Leptin, the rodents returned to full health.

This is an astonishing discovery because it strongly suggests that insulin is not the only substance that can combat diabetes.  This discovery could help control diabetes for longer periods of time.  Leptin could also not only eliminate liver damage, but could suppress hyperglycemia, ketoacidosis and weight loss. 

The research resulted in other stunning achievements.  Rodents that were in a diabetic coma and very near death were also treated with the leptin gene.  Their reaction to the Leptin was that they immediately started to produce massive amounts of leptin.  This counteracted the effects of diabetes, the rodents came out of the coma and their health came back to better than it had been before they were diagnosed with diabetes.    Rodents that were not treated with the leptin gene died within two to three days. 

Roger Unger, M.D., professor of internal medicine at Southwestern Medical Center in Utah, who directed the study, states that the next logical step in the research process should be to begin clinical trials within one year.  He notes that it is too soon to herald leptin as a cure for diabetes or a replacement for insulin, however, the study is significant in that it shows that it could work with insulin or eventually become a substitute for or replacement for insulin in the fight to control and overcome diabetes.

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