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There are many promising diabetes treatments on the medical horizon lately and most of them are helping individuals with diabetes.  There has been a discovery recently that some treatment can harm patients with diabetes and could even be fatal.

Glucose is an issue in diabetes, and there have been treatments designed to control glucose levels as well as controlling diabetes symptoms.  One treatment that addresses both situations is a combination treatment which uses two classes of drugs.  The problem is that researchers have found that there is an increased risk of mortality in patients who are given both drugs.

The problem was found by researchers who studied over 100,000 patients and discovered that the patients who received these two classes of drugs – meltformin and sulfonylureas – that combines to deal with the symptoms of both.
The problem is that these combine to create complications; many of them are cardiovascular issues.

What researchers found was astounding.  They found that there was a 19% increase of the people who took this combination therapy that had fatal outcomes.  They also found that there was a 29% increase in fatalities due to cardiac problems – most likely due to the interaction of the two medications.  The most important discovery was that there was a 43% increase in death or hospitalization due to cardiovascular issues in the group on combination therapy, even though all the groups had the same or similar health issues to begin with.

This is a significant study because the two medications used are the least expensive and the most widely used in combination to treat diabetes.  The study shows that there are more studies needed to determine why this happens, and it also shows that, at least for now, this combination of medications needs to be curtailed until there is more information and better outcomes.